Substrate: PDGF-R beta (Beta platelet-derived growth factor receptor)
Seq-ID: P05622 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-2832864   NHRF1_HUMAN
MINT-2832910   NHRF2_MOUSE
MINT-2832964   NHRF2_HUMAN
MINT-2833145   PTEN_MOUSE
MINT-6765460   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
vascular endothelial growth factor receptor activity,
ATP binding		 integral to plasma membrane skeletal system morphogenesis,
kidney development,
smooth muscle tissue development,
in utero embryonic development,
nitrogen compound metabolic process,
adrenal gland development,
regulation of peptidyl-tyrosine phosphorylation,
tissue homeostasis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 578 IESVSSDGHEYIYVDPVQLPY - 14966296
LTP
1.00
 - -
0.13
 - medium
Y 750 MDMSKDESIDYVPMLDMKGDI - 14966296
LTP
1.00
 - TyrKc
0.23
 - medium
Y 770 IKYADIESPSYMAPYDNYVPS - 14966296
LTP
1.00
 - TyrKc
0.24
 - medium
Y 856 LARDIMRDSNYISKGSTYLPL PDGFR_beta 2479827
LTP
1.00
 - TyrKc
0.10
 - medium
Y 1008 RSPLDTSSVLYTAVQPNESDN - 11940581
LTP
0.02
 - -
0.57
 - medium
Y 1020 AVQPNESDNDYIIPLPDPKPD - 14966296
LTP
1.00
 - -
0.74
 - medium

Substrate: PDGF-R beta (Beta platelet-derived growth factor receptor)
Seq-ID: P09619 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-2832596   NHRF2_HUMAN
MINT-2832984   PTEN_HUMAN
MINT-2833042   NHRF1_HUMAN
MINT-6762380   PTN1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
vascular endothelial growth factor receptor activity,
platelet-derived growth factor binding,
platelet activating factor receptor activity,
platelet-derived growth factor receptor binding,
ATP binding,
platelet-derived growth factor beta-receptor activity		 integral to plasma membrane positive regulation of cell proliferation,
positive regulation of cell migration,
protein amino acid autophosphorylation,
peptidyl-tyrosine phosphorylation,
cell chemotaxis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 562 LIMLWQKKPRYEIRWKVIESV PDGFR_beta 10821867
LTP
1.00
 - -
0.06
 - medium
Y 579 IESVSSDGHEYIYVDPMQLPY PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
SLA SH2;
Src SH2;
STAT5 SH2;
YES1 SH2		 -
0.15
 - medium
Y 581 SVSSDGHEYIYVDPMQLPYDS PDGFR_beta 8617789
LTP
1.00
 Fyn SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2;
RASA_group SH2;
SLA SH2;
Src SH2;
STAT5 SH2;
YES1 SH2		 -
0.16
 - medium
Y 716 DKRRPPSAELYSNALPVGLPL PDGFR_beta 8940081
LTP
1.00
 GRB2 SH2;
GRB7 SH2		 TyrKc
0.46
 - medium
Y 716 DKRRPPSAELYSNALPVGLPL PDGFR_beta 7935391
LTP
1.00
 GRB2 SH2;
GRB7 SH2		 TyrKc
0.46
 - medium
Y 740 VSLTGESDGGYMDMSKDESVD PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2		 TyrKc
0.45
 - medium
Y 751 MDMSKDESVDYVPMLDMKGDV PDGFR_beta 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
Src SH2		 TyrKc
0.29
 - medium
Y 751 MDMSKDESVDYVPMLDMKGDV PDGFR_group 8195171
LTP
1.00
 Fyn SH2;
NCK SH2;
PIK3R1 SH2;
PIK3R2 SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2;
Src SH2		 TyrKc
0.29
 - medium
Y 763 PMLDMKGDVKYADIESSNYMA - 10821867
LTP
0.28
 PTPN11 SH2 TyrKc
0.21
 - medium
Y 763 PMLDMKGDVKYADIESSNYMA PDGFR_beta N.N.
LTP
0.28
 PTPN11 SH2 TyrKc
0.21
 - medium
Y 763 PMLDMKGDVKYADIESSNYMA PDGFR_beta 10391677
LTP
0.28
 PTPN11 SH2 TyrKc
0.21
 - medium
Y 771 VKYADIESSNYMAPYDNYVPS PDGFR_beta 8195171
LTP
1.00
 CRK SH2;
PLCG1 SH2;
RASA_group SH2;
SHC1 SH2;
SHC_group SH2		 TyrKc
0.25
 - medium
Y 775 DIESSNYMAPYDNYVPSAPER PDGFR_beta 8940081
LTP
1.00
 GRB2 SH2;
GRB7 SH2;
STAT5 SH2		 TyrKc
0.34
 - medium
Y 778 SSNYMAPYDNYVPSAPERTCR PDGFR_beta 10821867
LTP
0.02
 - TyrKc
0.33
 - medium
Y 778 SSNYMAPYDNYVPSAPERTCR - 9394017
LTP
0.02
 - TyrKc
0.33
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_beta 10821867
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_group 10821867
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_beta 2550144
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 857 LARDIMRDSNYISKGSTFLPL PDGFR_group 2550144
LTP
1.00
 Fyn SH2;
RASA_group SH2;
Src SH2;
YES1 SH2		 TyrKc
0.08
 - medium
Y 1009 RSPLDTSSVLYTAVQPNEGDN PDGFR_beta 8195171
LTP
0.02
 NCK SH2;
PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2		 -
0.61
 - medium
Y 1021 AVQPNEGDNDYIIPLPDPKPE PDGFR_beta 12062403
LTP
1.00
 PIK3R1 SH2;
PLCG1 SH2;
PTPN11 SH2		 -
0.75
 - medium
S 1104 CPAPRAEAEDSFL         GRK-2 15271984
LTP
0.00
 - -
0.66
 - medium

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